You've got something basic going here, but there's a lot you can add. In terms of his history you should explore the circumstances of his parents' deaths, why the Templars would have cared to kill his sister (considering she was even younger than Leon and probably wouldn't posed too much of a threat), and about his training as an assassin and everything leading up to when you're playing him (about 12 years of training and...?). You also state he's an expert fighter and strategist but don't mention why he excels in these fields, which is something you could include beside the Strengths or, even better, in the biography. The only thing with your weaknesses is the gimpy wrist (should also explain how he got that) would probably be the cause for his bad climbing, which means you're kind of just stating the same thing again. You should also consider a reason for him being a good fighter with the wrist.
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